Calorie restriction induces weight loss, boosts insulin sensitivity

September 4, 2012

A new study in the journal Diabetes and Obesity Metabolism suggests that practicing calorie restriction or using a diet with calories reduced can lead to weight loss and improvement of insulin sensitivity in obese women with metabolic syndrome.

The study showed that 1 12-week calorie restriction resulted in a weight loss of 7.6 percent of baseline weight and improved insulin sensitivity by 49 percent.

Insulin resistance and visceral adiposity are associated with fatty liver disease, according to N.E. Straznicky of Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, Australia and colleagues who conducted the study.

The study was meant examine the association between caloric restriction alone or together with moderate-intensity aerobic exercise and liver enzymes, a surrogate marker of liver injury, in obese subjects with metabolic syndrome.

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